Rocaltrol is an effective medication used by people, who experience the following conditions:
Confirmed postmenopausal osteoporosis;
Renal osteodystrophy with chronic renal failure, and particularly are in hemodialysis;
Moderate or high degree of chronic renal failure (that is pre-dialysis) who suffer from secondary hyperparathyroidism;
Vitamin-D-dependent rickets and hypophosphatemic vitamin-D-resistant rickets (phosphate diabetes).
Rocaltrol Active Ingredient
The main ingredient of this remedy is calcitriol, which is one of the most useful and important active metabolites of the so much needed vitamin D3. Calcitriol provides intestinal absorption of calcium and regulates bone mineralization. Positive pharmacological effect of one calcitriol dose lasts up to 3-5 days, which is quite a long period.
The main role of calcitriol in the control of calcium metabolism, which consists in high stimulating of osteoblast activity of the bone skeleton, is a reliable pharmacological base for its long therapeutic effect for osteoporosis.
Contraindications and Dosing
All diseases that appear with hypercalcemia;
Hypersensitivity to the main component or to any other component of the drug;
Hypervitaminosis D, children up to 3 years old.
Presumably, calcitriol can appear in the breast milk. Taking into account possible hypercalcemia of the mother and adverse reactions of infants, the drug is not recommended during breastfeeding.
Patients should be careful while taking the remedy if they suffer from the following conditions:
Severe heart failure;
Severe sarcoidosis and other granulomatosis;
Old age (which may lead to development of dangerous atherosclerosis).
The initial daily dose is 0.25 mg. An optimal daily dose must be carefully selected for each patient depending on the calcium content in serum. The treatment must always begin with the smallest possible dose, and you shouldn’t increase it on your own, without the recommendation of your healthcare provider. Take the pills with a large amount of the water, with or without food.
Since Rocaltrol has an activity of vitamin D, the side effects of the remedy are similar to those that appear when there is vitamin D overdose, i.e. severe hypercalcemia syndrome or strong calcium intoxication (it depends on the severity and duration of hypercalcaemia). Other symptoms may include the following:
The following effects may occur after a long treatment:
Urinary tract infections.
However, if you take this particular remedy correctly, you will have no side effects and stay satisfied with the achieved result. Do not forget to take into consideration all the recommendations of your healthcare provider.